The EDV Breakthrough: EnGeneIC is the Game-Changer in Cancer Treatment

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Oct 2024

Recurrent pancreatic cancer treated with N-803 and PD-L1
t-haNK followed by an EGFR-targeted nanocell drug
conjugate

PDF
Oct 2024

A Phase 1 Study of Intravenous EGFR‑ErbituxEDVsMIT in Children
with Solid or CNS Tumours Expressing Epidermal Growth Factor
Receptor

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Mar 2024

Phase I/IIa Trial in Advanced Pancreatic Ductal
Adenocarcinoma Treated with Cytotoxic
Drug-Packaged, EGFR-Targeted Nanocells and
Glycolipid-Packaged Nanocells

PDF
Jan 2024

Nanocell COVID-19 vaccine triggers a novel immune response pathway producing high-affinity antibodies which neutralize all variants of concern.

Volume 13

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Jan 2023

Cyto-Immuno-Therapy for Cancer: A Pathway Elicited by Tumor-Targeted, Cytotoxic Drug-Packaged Bacterially Derived Nanocell.

Volume 37, Issue 3

Website · PDF
Mar 2020

RET kinase-regulated microRNA-153-3p improves therapeutic efficacy in medullary thyroid carcinoma

Volume 0, Issue JA
Website
Mar 2019

Targeted Doxorubicin-Loaded Bacterially Derived Nano-Cells for the Treatment of Neuroblastoma

Volume 17, Issue 5

Website · PDF

May 2018

Translational applications of microRNAs in cancer, and therapeutic Implications

Non-coding RNA Research 2: 143-150 (2017)

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Dec 2017

Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumor growth in mouse xenograft models

PLoS One. 12(10): 1-21 (2017)

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Oct 2017

Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma a first-in-man phase 1 open-label dose

Lancet Oncology 10: 1386-1396 (2017)

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Sept 2017

Clinical Development of TargomiRs, a miRNA mimic-based treatment for patients with recurrent thoracic cancer

Epigenomics 8: 1079-85 (2016)
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May 2016

Targeted Doxorubicin Delivery to Brain Tumors via Minicells: Proof of Principle Using Dogs with Spontaneously Occurring Tumors as a Model

PLoS One 11: 1-23 (2016)
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April 2016

A First-Time-In-Human Phase I Clinical Trial of Bispecific Antibody-Targeted, Paclitaxel-Packaged Bacterial Minicells

PLos One 10: 1-17 (2015)
Website · PDF
December 2015

First in human nanotechnology doxorubicin delivery system to target epidermal growth factor receptors in recurrent glioblastoma

Journal of Clinical Neuroscience; Volume 22; Issue 12; Pages: 1889-1894
Website · PDF
December 2015

microRNA-7 as a tumor suppressor and novel therapeutic for adrenocortical carcinoma

Oncotarget; Volume 6; Issue 34; Pages: 36675-88
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October 2015

A Significant Metabolic and Radiological Response after a Novel Targeted MicroRNA-based Treatment Approach in Malignant Pleural Mesothelioma

American Journal of Respiratory and Critical Care Medicine; Volume 191; Issue 12; Pages: 1467-1469
Website · PDF
June 2015

miR-193a-3p is a potential tumor suppressor in malignant pleural mesothelioma

Oncotarget; Volume 6; Issue 27; Pages: 23480-23495
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June 2015

Nanocell targeting using engineered bispecific antibodies

MAbs; Volume 7; Issue 1; Pages 53-65
Website · PDF
Jan/Feb 2015

Restoring expression of miR-16 a novel approach to therapy for malignant pleural mesothelioma

Annals of Oncology; Volume 24; Issue 12: Pages 3128-3135
Website · PDF
December 2013

New delivery option for anticancer drugs demonstrated in a clinical trial

Nanomedicine; Volume 8; Issue 1; Page 9
2013

Targeted Nanoparticle Delivery of Doxorubicin Into Placental Tissues to Treat Ectopic Pregnancies

Endocrinology Volume 154; Issue 2; Pages 911-919
Website · PDF
February 2013

Minicells: Versatile vectors for targeted drug or si/shRNA cancer therapy

Current Opinion in Biotechnology; Volume 22; Issue 6; Pages 909-916
Cover art designed by Dr. Himanshu Brahmbhatt and Dr. Jennifer MacDiarmid
Website · PDF
December 2011

Special Delivery

Nature Reviews Cancer; Volume 9
August 2009

Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug

Nature Biotechnology; Volume 27; Pages 643-651
Cover Art designed by Dr. Himanshu Brahmbhatt and Dr. Jennifer MacDiarmid
Website · PDF
2009

Minicells overcome tumor drug-resistance

Nature Biotechnology; Volume 27; Pages 620-621
Website · PDF
2009

Bacterially Derived Nanocells for Tumor Targeted Delivery of Chemotherapeutics and Cell Cycle Inhibitors

Cell Cycle| Volume 6, Issue 17: Pages 2099-2105
Website · PDF
September 2007

Minicells deliver lethal load to tumors

Nature Reviews Drug Discovery; Volume 6
July 2007

Bacterially Derived 400 nm Particles for Encapsulation and Cancer Cell Targeting of Chemotherapeutics

Cancer Cell | Volume 11, Issue 5: Pages 431-445
Website · PDF
May 2007